In a collaboration between the Sanger and Broad Institutes, variants in 10 genes have been associated with Crohn's disease. Alex is first author and more information can be found here.
Four members of the group made an appearance at #ECCO2022. Well done to Monika, Qian, Rofaida and Laura!
Michelle receives a "Star for Science" from the WGC for her contributions to education and public engagement. Well done Michelle!
IBD Edinburgh 2022 touches on all aspects of IBD from the bench to the bedside and Laura Fachal was invited as the event's IBD genetics expert. She presented upcoming GWAS meta-analysis and was on the expert panel.
After an excellent talk on splicing QTLs, Omar El Garwany was awarded the Charles J. Epstein Trainee Awards for Excellence in Human Genetics Research by the ASHG awards committee!
This is an excellent accomplishment so early in your PhD and well-earned! We're all delighted for you, Omar!
Sigurgeir's somatic mosaic Vitruvian man was chosen for the cover of this month's issue of Trends in Genetics. Within the issue is a review on the role of somatic mutations in complex disease by Sigurgeir and Carl, it can be read here.
The Anderson group has a strong showing at #ASHG2021, be sure to check out the following talks and posters:
Nikos - Genetics effects on expression upon immune stimulation in iPSC-derived macrophages enhance the discovery of putative causal disease genes.
Monika - Interpreting Genome-Wide Association Studies through the lens of single-cell sequencing
Omar - Splicing QTLs in iPSC-derived macrophages improve our understanding of complex disease
Sigurgeir - Whole-exome sequencing of hundreds of microbiopsies reveals the somatic evolutionary landscape of psoriatic skin
Laura - Expanded genome-wide association study of IBD identifies novel loci and
implicates new genes in disease susceptibility
Some of the latest results from our group's work as part of the International IBD Genetics Consortium will be presented at #DDW2021. Laura Fachal will present novel findings from expanded GWAS of IBD. 80 new risk loci found for IBD, effector genes identified from coding and non-coding susceptibility variants, with overlap with VEO-IBD genes. And work which Alex Sazonovs contributed to, WES of Crohn's disease patients, will be shared too.
As part of the Wellcome Genome Campus's public engagement efforts, Menna was invited to give a Genomics Lite lecture aimed at secondary schools. The talk was attended by over 100 students and teachers and is available on Youtube. For her exemplary contribution, Menna received a 'Stars for Science' award from the WGC!
The BBC were lucky enough to get the opportunity to interview our very own Ewan Harrison. Ewan has been on secondment to COG-UK as part of the Sanger’s contribution to the UK national SARS-CoV-2 genome sequencing consortium. Ewan's work has been crucial to the UK and worldwide efforts to track and control the pandemic. If you are interested, the entire interview can be found here.
Laura Fachal, previously our senior data scientist, has been promoted to senior staff scientist! In her new role she will be drawing together research from across the team and elsewhere in an effort to develop the ultimate GWAS machine. We are thrilled to see her getting the recognition she deserves and hope to keep her as part of the team for many more years.
Massive congratulations to Martin from everyone in Team Anderson! Thesis submitted, viva defended and we’re sure great things lie ahead for our latest soon-to-be graduated student.
Our long-serving senior staff scientist has received a well-deserved promotion! Rebecca will be the first Principal Staff Scientist in the Sanger Human Genetics Programme. She will continue to influence the Anderson Lab's research directions and manage the group's experimental team, whilst also working more closely with Sanger Faculty and the Anderson Lab's extensive network of collaborators to generate large 'omics datasets that will drive IBD research forward.
Following an excellent thesis and successful viva defence (with no corrections!), Ben is now Dr Bai! We are all very proud and wish him the best going forward.